RT Journal Article
SR Electronic
T1 Multi-Targeted Therapies in Non-Small Cell Lung Cancer
JF Clinical Oncology and Cancer Research
JO Cancer Biol Med
FD China Anti-Cancer Association
SP 220
OP 223
DO 10.1007/s11805-011-0584-6
VO 8
IS 4
A1 WANG, Kai
A1 WEI, Jin
YR 2011
UL http://www.cancerbiomed.org/content/8/4/220.abstract
AB Current treatment modalities provide limited improvement in the natural course of lung cancer, and prognosis remains poor. Lung cancer is a malignancy with great molecular heterogeneity. The complexity of the signaling process leading to cancer cell proliferation and to the neoplastic phenotype supports the necessity of interfering at different stages to avoid cancer cell resistance to therapy. For this reason, new strategies for the simultaneous inhibition of multiple molecular targets are being pursued.